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• Sales Rank: #4257502 in Books
• Published on: 1994
• Binding: Hardcover

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Ebook Free Trust Funnel: Leverage Today's Online Currency to Grab Attention, Drive and Convert Traffic, and Live a Fabulous Wealthy LifeBy Brian G.

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How does a dyslexic college dropout become an Internet marketing guru, living a life of wealth and freedom many people only dream of? Answer: by seeing a
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When his dad purchased a shiny new Apple 2E in 1983, it didn't take long for Brian G. Johnson to discover video games. He was hooked. However, what really
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• Sales Rank: #549397 in Books
• Published on: 2015-02-03
• Original language: English
• Number of items: 1
• Dimensions: 9.00" h x .57" w x 6.00" l, .0 pounds
• Binding: Paperback
• 250 pages

About the Author

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Free PDF Battered to BlessedBy Brenda Walsh

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Known to thousands of 3ABN viewers as “Miss Brenda,” the smiling children’s program host remembers a time when smiling wasn’t easy.

As a busy nursing student and “Miss Kentucky” beauty contestant, Brenda, at age 18, had a promising future of success, love, and happiness. But soon Brenda found herself at the mercy of a deceptive, cruel, and out-of-control man – threatening her very life.

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• Sales Rank: #990659 in eBooks
• Published on: 2011-06-08
• Released on: 2011-06-08
• Format: Kindle eBook

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Download PDF Hypatia's Heritage (Beacon Paperback)By Margaret Alic

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A History of Women in Science from Antiquity through the Nineteenth Century

• Sales Rank: #422832 in Books
• Brand: Brand: Beacon Press
• Published on: 1986-11-15
• Released on: 1986-11-15
• Original language: English
• Number of items: 1
• Dimensions: 8.50" h x .50" w x 5.50" l, .63 pounds
• Binding: Paperback
• 248 pages

Features

• Used Book in Good Condition

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PDF Ebook Geometric Algebra with Applications in Engineering (Geometry and Computing)By Christian Perwass

PDF Ebook Geometric Algebra with Applications in Engineering (Geometry and Computing)By Christian Perwass

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The application of geometric algebra to the engineering sciences is a young, active subject of research. The promise of this field is that the mathematical structure of geometric algebra together with its descriptive power will result in intuitive and more robust algorithms.

This book examines all aspects essential for a successful application of geometric algebra: the theoretical foundations, the representation of geometric constraints, and the numerical estimation from uncertain data. Formally, the book consists of two parts: theoretical foundations and applications. The first part includes chapters on random variables in geometric algebra, linear estimation methods that incorporate the uncertainty of algebraic elements, and the representation of geometry in Euclidean, projective, conformal and conic space. The second part is dedicated to applications of geometric algebra, which include uncertain geometry and transformations, a generalized camera model, and pose estimation.

Graduate students, scientists, researchers and practitioners will benefit from this book. The examples given in the text are mostly recent research results, so practitioners can see how to apply geometric algebra to real tasks, while researchers note starting points for future investigations. Students will profit from the detailed introduction to geometric algebra, while the text is supported by the author's visualization software, CLUCalc, freely available online, and a website that includes downloadable exercises, slides and tutorials.

• Sales Rank: #2306985 in Books
• Published on: 2008-12-16
• Original language: English
• Number of items: 1
• Dimensions: 9.30" h x .70" w x 6.30" l, 1.45 pounds
• Binding: Hardcover
• 386 pages

Review

From the reviews:

"This book shows how this geometric algebra relates to the more familiar concepts and how it can be applied to some engineering problems. … The book is organized in two parts--five chapters on theory and an equal number on applications. … Scientists and engineers will undoubtedly notice that they have seen cases and applications of the theorems and properties in more specific circumstances … . It will be useful for the nonmathematician … . It would be well worth the effort." (Anthony J. Duben, ACM Computing Reviews, June, 2009)

“The author introduces the principle of outer morphisms as generalizations of linear mappings in geometric algebras. … This book is a very nice, comprehensive and methodically perfected presentation of a new important branch of mathematics. The book shows there is no separation line between theoretical and applied mathematics. Mathematics has to be understood as a monolithic whole – this is one of the messages of this warmly recommended monography.” (Wolfgang Sprößig, Zentralblatt MATH, Vol. 1179, 2010)

“The book under review is an extensive introduction to geometric algebra and its various applications. Both the modern theory and recent results obtained by the author and his collaborators are included. … This book is intended for graduate students, academics and researchers interested in geometric algebra and its applications.” (Georgi Hristov Georgiev, Mathematical Reviews, Issue 2011 j)

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Download Ebook Pencil Sketches: Dickinson/WalserBy Josiah McElheny

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This publication brings together Robert Walser’s microscripts and Emily Dickinson’s poem manuscripts for the first time. Although Walser, who was born shortly before Dickinson died, was most likely unaware of her work, both writers were obsessively private as well as peculiarly attentive to the visual dimension of their texts. Walser wrote in tiny, inscrutable script on narrow strips of paper using an antiquated German alphabet that was long considered indecipherable. Only recently have these scripts been shown to consist of early drafts of the author’s published texts. Similarly, Dickinson fitted her poetic fragments to carefully torn pieces of envelope or stationery, which were discovered among her posthumous papers. (W.G. Sebald called Walser a "clairvoyant of the small," and this description might apply to Dickinson as well.) Rarely in literature has the manner in which words are made been so integral to the way they might be read.

• Sales Rank: #2532718 in Books
• Published on: 2014-04-30
• Original language: English
• Number of items: 1
• Dimensions: 9.00" h x 6.00" w x .50" l, .65 pounds
• Binding: Paperback
• 134 pages

About the Author
Robert Walser (1878 1956) was born in Switzerland. He left school at fourteen and led a wandering and precarious existence working as a bank clerk, a butler in a castle, and an inventor's assistant while producing essays, stories, and novels. In 1933 he abandoned writing and entered a sanatorium where he remained for the rest of his life. "I am not here to write," Walser said, "but to be mad."

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Free Ebook A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution

Free Ebook A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution

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A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution

Free Ebook A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution

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Audible Audiobook

Listening Length: 9 hours and 22 minutes

Program Type: Audiobook

Version: Unabridged

Publisher: Audible Studios

Audible.com Release Date: June 13, 2017

Whispersync for Voice: Ready

Language: English, English

ASIN: B072QWS8SJ

Amazon Best Sellers Rank:

More often than not, it’s difficult to determine which new titles will have staying power 10, 20 or 50 years from now. But “A Crack in Creation” deserves to be on any short list of decidedly important nonfiction books of 2017.The reason is not simply because of the authors’ pedigree — co-author Jennifer Doudna is credited as the chief pioneer behind CRISPR, the potentially world-changing gene-editing technique. The book’s impact is also buttressed by the authors’ scientific rigor, deeply felt passion, and understanding of the world-changing consequences of their research.Doudna and Samuel Sternberg’s “A Crack in Creation” is two books in one. The first third is a short primer on genetic engineering and the scientists who’ve advanced the science over the years. While the attention to detail and footnote-rich documentation is commendable, the lay reader will be forgiven if she skips through some of the dry backstory to get to the good stuff in the remaining two-thirds of the book. Because few of us have yet to reckon with the significant issues raised by the recent breakthroughs in CRISPR research, which only came to light in 2012.As the authors write:“Many experts predicted that CRISPR would be a research biologist’s dream come true, enabling experiments that one could have only fantasized about doing before. I imagined that it would democratize a technology that had once been the privilege of the few. … Now, CRISPR seemed to be on everyone’s lips and the topic of every conversation. And yet it was still only the tip of the iceberg. …“As I sat on the plane flying back to San Francisco after that first trip to Cambridge, I could already see a new era of genetic command and control on the horizon—an era in which CRISPR would transform biologists’ shared toolkit by endowing them with the power to rewrite the genome virtually any way they desired. Instead of remaining an unwieldy, uninterpretable document, the genome would become as malleable as a piece of literary prose at the mercy of an editor’s red pen.”Doudna’s initial worries centered on whether scientists would prematurely use CRISPR without proper oversight or consideration of the risks and whether bad actors might use the technology for nefarious purposes. So she took the first halting steps to begin a public dialogue about the implications of CRISPR research, first by organizing a roundtable of 17 scientists in January 2015 and then a larger gathering later that year to discuss gene therapy and germline enhancement. Those discussions continue to this day.Meantime, other researchers and entrepreneurs got busy. Entire companies have sprung up with the mission of conquering such genetic disorders as cystic fibrosis, sickle cell disease and Duchene muscular dystrophy. The reader roots along with the authors in cheering on what amounts to the beginning of what might be called “the precision genetic medicine revolution.”It’s helpful that the authors translate scientific arcana into everyday language, as when they mention that a snippet of DNA being modified by CRISPR is “roughly one one-thousandth the width of a human hair” or that a molecule “acted like a set of GPS coordinates” to guide the replacement DNA to the right spot or when referring to an enzyme as a “motorized hedge clipper.”Many readers will be interested in not today’s practical applications in the lab but in what tomorrow may herald. Count me in the latter category, as I just finished writing a suspense novel with CRISPR at the centerpiece. What’s so fascinating about the technology’s future prospects? The authors write:“In the future, parents may be offered the option of selecting for traits that go beyond disease susceptibility and gender and cross into areas like behavior, physical appearance, or even intelligence. The list of known associations between certain gene variants and a diverse list of traits continues to grow, and as the PGD technology improves further, what’s to stop fertility clinics from consulting this genetic information so they can offer their consumers even more choices when it comes to selecting the most desirable or ‘best’ embryos?”Entire conferences and mountains of newsprint will be devoted to dissecting the implications of CRISPR usage on early stage human embryos in the decades ahead. The door has just been cracked ajar.Where does Doudna, the progenitor of CRISPR, come down on the ethical scales?“I don’t believe there’s an ethical defense for banning germline modification outright, nor do I think we can justifiably prevent parents from using CRISPR to improve their chances of having a healthy, genetically related child, so long as the methods are safe and are offered in an equitable manner. … [But we also need to] redouble our commitment to building a society in which all humans are respected and treated equally, regardless of their genetic makeup. …“Advances in gene editing are enabling us to rewrite the very language of life—and putting us closer to gaining near-complete control of our genetic destiny. Together, we can choose how best to harness this technology There’s simply no way to unlearn this new knowledge, so we must embrace it. But we must do so cautiously, and with the utmost respect for the unimaginable power it grants us.”Well said. The authors smartly observe that society as a whole needs to be in on the decision on whether to move forward with certain aspects of the gene-editing revolution, and that scientists need to demystify the technology so the public can “understand their implications and decide how to use them.” Let the robust debate begin.

The late William Buckley claimed, "A conservative stands athwart history yelling, 'Stop!'" Dr Doudna is no conservative. Still, in "A Crack In Creation" she finds herself standing in the middle of the road of progress shouting, Wait! The book recounts her lab's discovery of how a highly adaptable region of bacterial DNA called the clustered regularly interspaced short palindromic repeats (CRISPR) can be programed to edit DNA itself. Potentially, CRISPR gene editing will cure many human diseases and end much suffering.Amid all the excitement a dream in which she meets Adolph Hitler compelled Dr Doudna to ask the Frankenstein question: Just because we can do something (in this instance, edit the human germline), does that mean we should? In a collection of essays entitled "From Under the Rubble," Nobel laureate Alexander Solzhenitsyn presents the image of technologists running hard to both keep up and stay ahead. They're running hard just to keep pace--heads down and tongues lolling, panting and sweating to stay ahead of the researcher on their heels while trying to overtake the researcher just ahead. But they never take the time to ask IF their research ought to proceed.All credit is due Dr Doudna for exclaiming, Wait! We need to talk this through; this issue is too big for just science. Yes, she comes down on the side of racing forward. But the way she thinks through this potentially humanity changing science helped me see gene editing not just with layman's knowledge, but with compassion and a bit wider perspective than when I started the book. And yet ... while she pays polite lip service to potential religious concerns about gene editing, her embrace of random evolution leads her to view religious objections as antiquated notions that need only be addressed to be disposed.Scientists (actually, their editors) writing for layman ought to include a glossary. That's missing. And her habit of expressing how brilliant her fellow scientists are gets pretty worn pretty fast. Regardless, A Crack In Creation deserves your attention. ~Star Readers: from out of the east

While the writing and presentation gives a sense of having been rushed out, and first part is a tough slog for a lay person, there is no doubt as to the importance of the issues raised in the 2nd and 3rd parts that should be elevated to a global dialogue. My mind immediately went back to the movie Gattaca in depicting what the future might look like for a genetically engineered human race (and admittedly, this may have contributed to my views below) - after all, what we are talking about with gene editing and germline editing is, or was for me, science fiction.The author's sometimes apparent (to me) hubris needs to be carefully balanced against the awesome power and "unknown unknowns" this technology may bring to humanity, e.g. a few passages leapt out, such as blithe dismissal of the likelihood of humans repeating the dark history of eugenics. Nevertheless, I believe the author is aiming to do good and this is an important contribution in shining a light in this area - I was surprised (and shocked) that science had progressed so far and so quickly, at least to me, without significant public debate or governmental intervention.

Fascinating subject, but the book is not particularly well written and frankly its way too technical, filled with a lot info you don't really need to absorb the enormity of this discovery. But thank you Jennifer Doudna and all the researchers who have spent years fine tuning this technique, I have no doubt you will save many lives. I can't imagine how to ensure that it's only used for good, not evil purposes.

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A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution PDF

A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution PDF

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